Plasma cell leukemia presenting as “lymphocytosis”
نویسندگان
چکیده
منابع مشابه
Primary plasma cell leukemia presenting as a thoracic mass
Primary Plasma cell leukaemia (pPCL) is a rare plasma cell (PC) malignancy. The strict criteria for the diagnosis is an absolute PC number greater 2 × 10(9)/L or a plasmocytosis accounting for > 20% of the differential white cell count that does not arise from a pre-existing multiple myeloma. pPCL was associated with aggressive clinic-biological features. Primary Plasma cell leukaemia is more c...
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A 50-year-old female with low-grade chronic anemia and no other medical problems was evaluated when her hemoglobin fell to 8.2 g/dL. She had no adenopathy or hepatosplenomegaly. Her white cell count was 7.7 109/L with a lymphocyte count of 6.2 109/L, platelets 498 109/L, and reticulocyte count that was normal. Serum electrophoresis and rheumatoid factor were negative and ANA was weakly positive...
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A 55-year-old man was admitted with fever and rapidly progressive renal failure with serum creatinine levels of 6.5 mg/dL and blood urea of 98 mg/dL. Complete blood counts revealed a hemoglobin of 50 g/L, a leukocyte count of 13.3 3 10/L, and a platelet count of 46 3 10/L. Peripheral blood smear examination showed clusters of cells dispersed throughout the smear (panels A-D). These clusters wer...
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Plasma cell leukemia (PCL) is an uncommon neoplasm of plasma cells, with an aggressive clinical course and poor outcome, even with current standard of care. It can occur either de novo (primary PCL) or as a progression of multiple myeloma (MM). This disease has unique diagnostic criteria but certain genetic markers and clinical features may overlap with MM. Due to the low prevalence of PCL, gui...
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Plasma cell myeloma (PCM) is a malignant hematologic disease characterized by the proliferation of neoplastic plasma cells, producing excessive amounts of monoclonal immunoglobulin (Ig) or light chain (LC) [1, 2]. Although plasma cells are widely distributed throughout the body, PCM is found most often within the bone and bone marrow (BM), while the dissemination of extramedullary plasmacytoma ...
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ژورنال
عنوان ژورنال: Blood
سال: 2018
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2018-02-831230